C5 Drug Candidate Efficacy & Toxicity
Aug 1, 2025·
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1 min read
Meghan Forsythe
Evaluating C5 BCX candidates for efficacy and toxicity: Internship at BioCryst Pharmaceuticals.Abstract
During my Summer Internship at BioCryst Pharmaceuticals, I gained hands-on experience with industry drug discovery and assay development. My project focused on evaluating C5 BCX candidates for efficacy and toxicity using cutting-edge laboratory methods.
Type
Publication
BioCryst Pharmaceuticals Summer Internship Presentation
Project Overview
BioCryst Pharmaceuticals Summer Internship provided comprehensive training in drug development and laboratory skills. The main goal was to evaluate C5 BCX drug candidates for both efficacy and toxicity using industry-standard assays.
Techniques and Results
- Developed AP ELISA assay for functional drug candidate measurement.
- Performed ZMAC30 assay for toxicity and off-target effect assessment.
- Maintained and utilized tissue culture models to validate results.
Internship Experience
This internship allowed for a deep understanding of the pharmaceutical workflow, from early-stage candidate evaluation to hands-on assay development and presentation to industry peers.
Media


Acknowledgements
Special thanks to the BioCryst mentors and lab team for providing training and support throughout this internship.